Dectin-2 Polyclonal Antibody - BT-AP02556

Dectin-2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02556-20, BT-AP02556-50, BT-AP02556-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by CLEC6A (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for CLEC6A.

Research Areas: Immunology

Target Protein: CLEC6A

Applications: WB, IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Dectin-2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 23998

UniProt Accession: Human: Q6EIG7; Mouse: Q9JKF4

Synonyms: CLEC6A; CLECSF10; DECTIN2; C-type lectin domain family 6 member A; C-type lectin superfamily member 10; Dendritic cell-associated C-type lectin 2; DC-associated C-type lectin 2; Dectin-2

GeneID: Human: 93978

Research Use Only