Desmin Monoclonal Antibody - BT-MCA4620

Desmin Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4620-50, BT-MCA4620-100

Citations, Manuals and MSDS Available upon request.

Background: Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

Research Areas: Others

Target Protein: Desmin

Applications: WB, IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 10H7D2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: Desmin

Immunogen: Purified recombinant fragment of Desmin expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS containing 0.03% sodium azide.

UniProt Accession: P17661

Synonyms: Desmin

GeneID: 1674

Research Use Only