Product Description

DHB2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES9653-50, ES9653-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: catalytic activity:Estradiol-17-beta + NAD(P)(+) = estrone + NAD(P)H.,catalytic activity:Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH.,function:Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: DHB2

Specificity: DHB2 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Expressed in placenta,

Observed Band (KD): 42kD

Fields: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis

Function: Catalytic Activity: Estradiol-17-beta + NAD(P)(+) = estrone + NAD(P)H
Catalytic Activity: Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH
Function: Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Subcellular Location: Endoplasmic reticulum membrane, Single-pass type II membrane protein

Storage and Stability: -20°C/1 year

Gene Name: HSD17B2 EDH17B2

Protein Name: Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Microsomal 17-beta-hydroxys

Mouse SwissProt Number: P51658

Rat SwissProt Number: Q62730

Research Use Only