Product Description

DHB8 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15234-20, BT-AP15234-50, BT-AP15234-100

Citations, Manuals and MSDS Available upon request.

Background: In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Research Areas: Neuroscience; Signal transduction

Target Protein: HSD17B8

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Estradiol 17-beta-dehydrogenase 8

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q92506; Mouse: P50171; Rat: Q6MGB5

Synonyms: Estradiol 17-beta-dehydrogenase 8;EC 1.1.1.62;17-beta-hydroxysteroid dehydrogenase 8;17-beta-HSD 8;3-oxoacyl-[acyl-carrier-protein] reductase;EC 1.1.1.-;Protein Ke6;Ke-6;Really interest

GeneID: Human: 7923

Research Use Only