DHX58 Polyclonal Antibody - BT-AP15235

DHX58 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15235-20, BT-AP15235-50, BT-AP15235-100

Citations, Manuals and MSDS Available upon request.

Background: Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP-binding domain.,Contains 1 helicase C-terminal domain.,subunit:Interacts with DDX58 and probably blocks its homomultimerization.,

Research Areas: Epigenetics and nuclear signaling; Immunology

Target Protein: DHX58

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Probable ATP-dependent RNA helicase DHX58

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q96C10; Mouse: Q99J87

Synonyms: Probable ATP-dependent RNA helicase DHX58;EC 3.6.4.13;Probable ATP-dependent helicase LGP2;Protein D11Lgp2 homolog;RIG-I-like receptor 3;RLR-3;RIG-I-like receptor LGP2;RLR

GeneID: Human: 79132

Research Use Only