Dkk-3 Polyclonal Antibody - BT-AP02624

Dkk-3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02624-20, BT-AP02624-50, BT-AP02624-100

Citations, Manuals and MSDS Available upon request.

Background: DKK3 encodes dickkopf WNT signaling pathway inhibitor 3 that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of DKK3 is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.

Research Areas: Signal Transduction

Target Protein: DKK3

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Dkk-3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 38291

UniProt Accession: Human: Q9UBP4; Mouse: Q9QUN9

Synonyms: DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3

GeneID: Human: 27122; Mouse: 50781

Research Use Only