DLK1 Monoclonal Antibody - BT-MCA2035

DLK1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2035-50, BT-MCA2035-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

Research Areas: Signal transduction, Neuroscience, Stem cells

Target Protein: DLK1

Applications: ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3A10

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: DLK1

Immunogen: Purified recombinant fragment of human DLK1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 41kDa

UniProt Accession: P80370

Synonyms: DLK, FA1, ZOG, pG2, PREF1, Pref-1

GeneID: 8788

Research Use Only