DLRB1 Polyclonal Antibody - BT-AP08517

DLRB1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08517-20, BT-AP08517-50, BT-AP08517-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.

Research Areas: Cancer; Signal transduction

Target Protein: DYNLRB1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Dynein light chain roadblock-type 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9NP97; Mouse: P62627; Rat: P62628

Synonyms: Dynein light chain roadblock-type 1;Bithoraxoid-like protein;BLP;Dynein light chain 2A, cytoplasmic;Dynein-associated protein Km23;Roadblock domain-containing protein 1

GeneID: Human: 83658

Research Use Only