DNA pol Gamma2 Polyclonal Antibody - BT-AP02657

DNA pol Gamma2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02657-20, BT-AP02657-50, BT-AP02657-100

Citations, Manuals and MSDS Available upon request.

Background: POLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: POLG2

Applications: IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: DNA pol gamma2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 54911

UniProt Accession: Human: Q9UHN1; Mouse: Q9QZM2

Synonyms: POLG2; MTPOLB; DNA polymerase subunit gamma-2; mitochondrial; DNA polymerase gamma accessory 55 kDa subunit; p55; Mitochondrial DNA polymerase accessory subunit; MtPolB; PolG-beta

GeneID: Human: 11232

Research Use Only