DNA2 Polyclonal Antibody - BT-AP15255

DNA2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15255-20, BT-AP15255-50, BT-AP15255-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene.

Research Areas: Epigenetics and nuclear signaling

Target Protein: DNA2

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: DNA replication ATP-dependent helicase/nuclease DNA2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P51530; Mouse: Q6ZQJ5; Rat: D3ZG52

Synonyms: DNA replication ATP-dependent helicase/nuclease DNA2;hDNA2;DNA replication ATP-dependent helicase-like homolog [Includes: DNA replication nuclease DNA2;EC 3.1.-.-; DNA replication ATP-dependent

GeneID: Human: 1763

Research Use Only