Product Description

DNMT1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20983-50, RA20983-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: DNA methyltransferase 1 (DNMT1) Homo sapiens This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 177

Protein Molecular Weight (kDa): 177

Storage: -20°C/1 year

Human Gene ID: 1786

Human SwissProt Number: P26358

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only