DOCK 2 Polyclonal Antibody - BT-AP02693

DOCK 2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02693-20, BT-AP02693-50, BT-AP02693-100

Citations, Manuals and MSDS Available upon request.

Background: Dedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection.

Research Areas: Others

Target Protein: DOCK2

Applications: IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: DOCK 2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 211948

UniProt Accession: Human: Q92608; Mouse: Q8C3J5

Synonyms: DOCK2; KIAA0209; Dedicator of cytokinesis protein 2

GeneID: Human: 1794; Mouse: 94176

Research Use Only