DOCK1 Rabbit pAb - A17359

DOCK1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A17359-20, A17359-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human

Protein Weight: 215kDa

Observed Molecular Weight: 215kDa

Immunogen: Synthetic peptide

Species: Human

GeneID: 1793

SWISS: B2RUU3

Alternate Names: ced5; DOCK180; DOCK1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism.

NCBI Alias: DOCK1

Research Use Only