DOCK1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A17359-20, A17359-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 215kDa
Observed Molecular Weight: 215kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 1793
SWISS: B2RUU3
Alternate Names: ced5; DOCK180; DOCK1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism.
NCBI Alias: DOCK1
Research Use Only