Dok-2 Polyclonal Antibody - BT-AP02698

Dok-2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02698-20, BT-AP02698-50, BT-AP02698-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

Research Areas: Signal Transduction

Target Protein: DOK2

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Dok-2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 45379

UniProt Accession: Human: O60496; Mouse: O70469

Synonyms: DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2)

GeneID: Human: 9046; Mouse: 13449

Research Use Only