Dok-6 (G130) Polyclonal Antibody-BS2488

Dok-6 (G130) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS2488-50, BS2488-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q6PKX4

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC, IF

All Applications: IHC: 1:50~1:200
IF: 1:50~1:200

Background: The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of Dok-6 (G130) pAb in paraffin-embedded human brain tissue.

Bioworld Molecular Weight: ~ 43 kDa

Specificity: Dok-6 (G130) polyclonal antibody detects endogenous levels of Dok-6 protein.

Alternative Name: Docking protein 6; Downstream of tyrosine kinase 6; DOK5L; docking protein 5-like

Immunogen: Synthetic peptide, corresponding to amino acids 98-149 of Human Dok-6.

Conjugate: Unconjugated

Modification: Unmodified