DOK5 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13726-20, A13726-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 35kDa
Observed Molecular Weight: 30kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 55816
SWISS: Q9P104
Alternate Names: IRS6; IRS-6; C20orf180; DOK5
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Kinase, Tyrosine kinases.
NCBI Alias: DOK5
Research Use Only