DOR-1 (R356) Polyclonal Antibody-BS1814

DOR-1 (R356) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS1814-50, BS1814-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P41143

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: The opioid receptors are G-protein coupled, seven-transmembrane domain receptors for enkephalins, endorphins, and dynorphins. Three different opioid receptor subtypes (kappa , delta, and mu) were first identified by their different selectivities for various naturally occurring alkaloid opioid ligands, and subsequently confirmed by molecular cloning. The amino acid sequences of the opioid receptor subtypes are ~70% homologous, and are similar to somatostatin receptors (SSTRs) showing ~40 % homology with SSTR1. G-protein binding is thought to occur at the third intracellular loop of the opioid receptors, which is also the location of consensus sequences for phosphorylation of the receptor. Interestingly, the genes encoding the specific receptor subtypes are found on different chromosomes in both the human and mouse genomes.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of DOR-1 (R356) pAb in paraffin-embedded human brain tissue.

Bioworld Molecular Weight: ~ 35, 50 kDa

Specificity: DOR-1 (R356) polyclonal antibody detects endogenous levels of DOR-1 protein.

Alternative Name: Delta-type opioid receptor; D-OR-1; DOR-1; OPRD1; OPRD

Immunogen: Synthetic peptide, corresponding to amino acids 320-370 of Human DOR-1.

Conjugate: Unconjugated

Modification: Unmodified