Product Description

DPYSL4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65335-50, BS65335-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: disease:Antibodies against post-translationally modified DPYSL4, also called anti-CV2 autoantibodies, are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct resμlt of the tumor mass or metastasis, but attributed to remote effects of the cancer., function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily., subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1.,

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: DPYSL4, CRMP3,μlIP4, Dihydropyrimidinase-related protein 4, DRP-4, Collapsin response mediator protein 3, CRMP-3, UNC33-like phosphoprotein 4,μlIP-4

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: The antiserum was produced against synthesized peptide derived from human DPYSL4. AA range:91-140

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: CRMP-3 Polyclonal Antibody detects endogenous levels of CRMP-3 protein.

Molecular Weight: ~ 62 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O14531

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only