Product Description

DRAM1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES11436-50, ES11436-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human protein. at AA range: 151-200

Isotype: IgG

Target: DRAM1

Specificity: DRAM1 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Observed Band (KD): 26kD

Function: autophagy, apoptosis, cell death, programmed cell death, death,

Subcellular Location: Lysosome membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: DRAM1 DRAM

Protein Name: DNA damage-regulated autophagy modulator protein 1 (Damage-regulated autophagy modulator)

Mouse SwissProt Number: Q9DC58

Research Use Only