Product Description

DREG Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES2201-50, ES2201-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF, ELISA

Alternate Names: GPR126, DREG, VIGR, G-protein coupled receptor 126, Developmentally regulated G-protein-coupled receptor, Vascular inducible G protein-coupled receptor

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human GPR126. AA range:1091-1140

Isotype: IgG

Target: DREG

Specificity: DREG Polyclonal Antibody detects endogenous levels of DREG protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in placenta and to a lower extent in pancreas and liver, Detected in aortic endothelial cells but not in skin microvascular endothelial cells,

Observed Band (KD): 140kD

Function: Function: Orphan receptor
polymorphism: Genetic variations in GPR126 influences stature as a quantitative trait (STQTL) [MIM: 606255]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits
Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily
Similarity: Contains 1 CUB domain
Similarity: Contains 1 GPS domain
Similarity: Contains 1 pentaxin domain

Subcellular Location: Cell membrane, Multi-pass membrane protein Detected on the cell surface of activated but not resting umbilical vein

Storage and Stability: -20°C/1 year

Gene Name: GPR126

Protein Name: G-protein coupled receptor 126

Mouse Gene ID: 215798

Mouse SwissProt Number: Q6F3F9

Research Use Only