DUS14 Polyclonal Antibody - BT-AP15333

DUS14 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15333-20, BT-AP15333-50, BT-AP15333-100

Citations, Manuals and MSDS Available upon request.

Background: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009

Research Areas: Signal transduction

Target Protein: DUSP14

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Dual specificity protein phosphatase 14

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O95147; Mouse: Q9JLY7

Synonyms: Dual specificity protein phosphatase 14;EC 3.1.3.16;EC 3.1.3.48;MKP-1-like protein tyrosine phosphatase;MKP-L;Mitogen-activated protein kinase phosphatase 6;MAP kinase phosphatase 6;MKP-6

GeneID: Human: 11072

Research Use Only