Product Description

DUSP27 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65439-50, BS65439-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellμlar stresses, thereby negatively regμlating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1, 200 genes and comprises nearly 4.5% of the human genome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep

Host: Rabbit

Applications: WB

Alternate Names: Atypical dual specific protein phosphatase, Dual specificity phosphatase 27, Dual specificity phosphatase and pro isomerase domain containing 1, Dual specificity phosphatase DUPD1, dupd1, DUPD1_HUMAN, DUSP27, OTTHUMP00000019871.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human DUSP27:21-120/220

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: DUSP27 Polyclonal Antibody detects endogenous levels of DUSP27 protein.

Molecular Weight: 27 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q68J44

Product: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Research Use Only