Product Description

DUX5 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES10628-50, ES10628-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: double homeobox 5(DUX5) Homo sapiens The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX5, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human protein. at AA range: 10-90

Isotype: IgG

Target: DUX5

Specificity: DUX5 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Expressed in hepatoma Hep3B cells,

Observed Band (KD): 21kD

Function: Developmental Stage: Expressed in fetal tissue
Domain: Homebox domain 2 confers nuclear targeting
Function: Probable transcription activator. Binds the P5 DNA element sequence 5'-GATCTGAGTCTAATTGAGAATTACTGTAC-3'
Miscellaneous: DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes
Miscellaneous: DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. May be functional despite lack of introns and a poly(A) addition signal
Similarity: Belongs to the paired homeobox family
Similarity: Contains 2 homeobox DNA-binding domains
Subcellular Location: Actively transported through the nuclear pore complex (NPC)
Tissue Specificity: Ex

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: DUX5

Protein Name: Double homeobox protein 5

Research Use Only