Product Description

DYN3 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES11026-50, ES11026-100

Lead times: approximately 7-10 business days, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: dynamin 3(DNM3) Homo sapiens This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: DYN3,

Specificity: DYN3 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Brain, Kidney,

Observed Band (KD): 95kD

Fields: Phospholipase D signaling pathway, Endocytosis, Synaptic vesicle cycle, Endocrine and other factor-regulated calcium reabsorption, Bacterial invasion of epithelial cells

Function: Catalytic Activity: GTP + H(2)O = GDP + phosphate. Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis. Similarity: Belongs to the dynamin family. Similarity: Contains 1 GED domain. Similarity: Contains 1 PH domain. Subcellular Location: Microtubule-associated.

Subcellular Location: Cytoplasm Cytoplasm, cytoskeleton Microtubule-associated.

Storage and Stability: -20°C/1 year

Gene Name: DNM3, KIAA0820

Protein Name: Dynamin-3, EC 3.6.5.5, Dynamin, testicular, T-dynamin

Human Gene ID: 26052

Human SwissProt Number: Q9UQ16

Mouse SwissProt Number: Q8BZ98

Rat SwissProt Number: Q08877

Research Use Only