Dynamin-1 Monoclonal Antibody - BT-MCA3362

Dynamin-1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3362-50, BT-MCA3362-100

Citations, Manuals and MSDS Available upon request.

Background: Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.

Research Areas: Others

Target Protein: Dynamin-1

Applications: WB, IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3G4B6

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: Dynamin-1

Immunogen: Purified recombinant fragment of human Dynamin-1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 97kDa

UniProt Accession: Q05193

Synonyms: DNM, DNM1

GeneID: 1759

Research Use Only