DYNC2LI1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A4752-20, A4752-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15) . Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 40kDa
Observed Molecular Weight: 38kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 51626
SWISS: Q8TCX1
Alternate Names: LIC3; D2LIC; CGI-60; DYNC2LI1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Cytoskeleton, Motor Proteins.
NCBI Alias: DYNC2LI1
Research Use Only