Dynein IC1 Polyclonal Antibody - BT-AP02767

Dynein IC1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02767-20, BT-AP02767-50, BT-AP02767-100

Citations, Manuals and MSDS Available upon request.

Background: DNAI1 encodes a member of the dynein intermediate chain family. The dynein axonemal intermediate chain 1 is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.

Research Areas: Neuroscience

Target Protein: DNAI1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Dynein IC1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 79283

UniProt Accession: Human: Q9UI46; Mouse: Q8C0M8; Rat: Q5XIL8

Synonyms: DNAI1; Dynein intermediate chain 1; axonemal; Axonemal dynein intermediate chain 1

GeneID: Human: 27019; Mouse: 68922; Rat: 500442

Research Use Only