Product Description

EARS2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18191-60, E-AB-18191-120, E-AB-18191-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: EARS2

Target Synonym: 3230401I01Rik; AL024049; COXPD12; EARS 2; ears2; GluRS; Glutamate--tRNA ligase; Glutamyl tRNA synthetase 2 mitochondrial; mitochondrial; mKIAA1970; MSE1; Probable glutamyl tRNA synthetase; mitochondrial ; Probable glutamyl-tRNA synthetase; RGD1307904; SYEM

Research Areas: Epigenetics and Nuclear Signaling, Metabolism, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q5JPH6

Background: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.

Concentration: 0.9 mg/mL

Immunogen: Synthetic peptide of human EARS2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only