ECE2 Polyclonal Antibody - BT-AP15356

ECE2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15356-20, BT-AP15356-50, BT-AP15356-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.

Research Areas: Cardiovascular; Neuroscience; Signal transduction

Target Protein: ECE2

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Endothelin-converting enzyme 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O60344; Mouse: Q80Z60

Synonyms: Endothelin-converting enzyme 2;ECE-2 [Includes: Methyltransferase-like region;EC 2.1.1.-; Endothelin-converting enzyme 2 region;EC 3.4.24.71]

GeneID: Human: 9718

Research Use Only