EDC4 Polyclonal Antibody - BT-AP15368

EDC4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15368-20, BT-AP15368-50, BT-AP15368-100

Citations, Manuals and MSDS Available upon request.

Background: In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the Catalytic activity of DCP2 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the WD repeat EDC4 family.,Contains 4 WD repeats.,subunit:Part of a decapping complex consisting of DCP1A, DCP2, EDC3, EDC4 and probably DDX6. Part of a complex consisting of DCP1A, EDC3, EDC4 and DDX6. Part of a complex consisting of DCP1B, EDC3, EDC4 and DDX6. Interacts with DCP2.,

Research Areas: Epigenetics and nuclear signaling

Target Protein: EDC4

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Enhancer of mRNA-decapping protein 4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q6P2E9; Mouse: Q3UJB9; Rat: Q3ZAV8

Synonyms: Enhancer of mRNA-decapping protein 4;Autoantigen Ge-1;Autoantigen RCD-8;Human enhancer of decapping large subunit;Hedls

GeneID: Human: 23644

Research Use Only