EDN1 Monoclonal Antibody - BT-MCA2424

EDN1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2424-50, BT-MCA2424-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Research Areas: Signal Transduction

Target Protein: EDN1

Applications: ICC, FCM

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 4E6E5

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: EDN1

Immunogen: Purified recombinant fragment of human EDN1 (AA: 18-212) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 24.4KDa

UniProt Accession: P05305

Synonyms: ET1, QME, PPET1, ARCND3, HDLCQ7

GeneID: 1906

Research Use Only