eEF2K Polyclonal Antibody - BT-AP02842

eEF2K Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02842-20, BT-AP02842-50, BT-AP02842-100

Citations, Manuals and MSDS Available upon request.

Background: EEF2K encodes a highly conserved protein kinase (eukaryotic elongation factor 2 kinase) in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of eukaryotic elongation factor 2 kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: EEF2K

Applications: WB, IHC-p, ELISA

Reactivity: Human, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: eEF2K Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 82172

UniProt Accession: Human: O00418; Mouse: O08796; Rat: P70531

Synonyms: EEF2K; Eukaryotic elongation factor 2 kinase; eEF-2 kinase; eEF-2K; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase

GeneID: Human: 29904; Rat: 25435

Research Use Only