Product Description

EF1D Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES9641-50, ES9641-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: eukaryotic translation elongation factor 1 delta(EEF1D) Homo sapiens This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: EF1D

Specificity: EF1D Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Isoform 2 is specifically expressed in brain, cerebellum and testis,

Observed Band (KD): 30kD

Function: Function: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR
Similarity: Belongs to the EF-1-beta/EF-1-delta family
Subunit: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma

Subcellular Location: [Isoform 2]: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: EEF1D EF1D

Protein Name: Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4)

Mouse SwissProt Number: P57776

Rat SwissProt Number: Q68FR9

Research Use Only