EFGM Polyclonal Antibody - BT-AP15372

EFGM Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15372-20, BT-AP15372-50, BT-AP15372-100

Citations, Manuals and MSDS Available upon request.

Background: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.

Research Areas: Epigenetics and nuclear signaling; Metabolism; Signal transduction

Target Protein: GFM1

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Elongation factor G, mitochondrial

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q96RP9; Mouse: Q8K0D5; Rat: Q07803

Synonyms: Elongation factor G, mitochondrial;EF-Gmt;Elongation factor G 1, mitochondrial;mEF-G 1;Elongation factor G1;hEFG1

GeneID: Human: 85476

Research Use Only