Product Description

EIF2AK1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65236-50, BS65236-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: Q9BQI3

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, IF (paraffin section), ELISA

All Applications: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Background: eukaryotic translation initiation factor 2 alpha kinase 1(EIF2AK1) Homo sapiens The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HRI Polyclonal Antibody detects endogenous levels of HRI protein.

Bioworld Molecular Weight: ~ 71 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of various cells using HRI Polyclonal Antibody, Western blot analysis of lysates from A549 and COS7 cells, using EIF2AK1 Antibody. The Lane on the right is blocked with the synthesized peptide., Western blot analysis of the lysates from COLO205 cells using EIF2AK1 antibody.

Alternative Name: EIF2AK1; HRI; KIAA1369; Eukaryotic translation initiation factor 2-alpha kinase 1; Heme-controlled repressor; HCR; Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; Heme-regulated inhibitor; Hemin-sensitive initiation factor 2

Immunogen: The antiserum was produced against synthesized peptide derived from human EIF2AK1. AA range:571-620

Conjugate: Unconjugated

Modification: Unmodified