EIF2AK3 Monoclonal Antibody - BT-MCA3889

EIF2AK3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3889-50, BT-MCA3889-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: EIF2AK3

Reactivity: Human

Clonality: Monoclonal

Clone ID: 5G5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: EIF2AK3

Immunogen: Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 125kDa

UniProt Accession: Q9NZJ5

Synonyms: PEK, WRS, PERK, EIF2AK3

GeneID: 9451

Research Use Only