Product Description

eIF5B (H1086) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3125-50, BS3125-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of mμltiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Eukaryotic translation initiation factor 5B, Translation initiation factor IF2, IF2, FLJ10524, KIAA0741, DKFZp434I036, Translation initiation factor IF 2, eIF 5B

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 1061-1110 of Human eIF5B.

Dilution: IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: eIF5B (H1086) polyclonal antibody detects endogenous levels of eIF5B protein.

Molecular Weight: ~ 139 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O60841

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only