Product Description

ELF1 (E573) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1979-50, BS1979-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1–3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA-binding activity of all members of the Ets gene family. Elf-1 is a lymphoid-specific member of the Ets family that has been shown to regμlate inducible gene expression during T cell activation. Elf-1 contains a sequence motif that is highly related to the Rb-binding sites common to several viral oncoproteins and binds to the pocket region of Rb both in vivo and in vitro.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC

Alternate Names: E74 like factor 1, E74-like factor 1, ELF 1, ELF1, ELF1, Ets domain transcription factor, ETS related transcription factor Elf 1, ETS related transcription factor Elf1, ets-related transcription factor, ETS-related transcription factor Elf-1, mElf 1,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids C-terminus of Human Elf-1.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Elf-1 (E573) polyclonal antibody detects endogenous levels of Elf-1 protein.

Molecular Weight: ~ 67 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P32519

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only