Endophilin B2 Polyclonal Antibody - BT-AP02960

Endophilin B2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02960-20, BT-AP02960-50, BT-AP02960-100

Citations, Manuals and MSDS Available upon request.

Background: The Endophilins comprise a family of proteins that associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the Endophilins are consistent with their cellular functions at the neuronal synapse. Endophilin B1 is a member of the B subgroup of the Endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics. Endophilin B2 is also a member of the Endophilin B subroup that is ubiquitously expressed but shows highest levels in brain, adult lung, ovary, and spinal cord. Decreased levels of Endophilin B2 are found in Down Syndrome and may reflect brain dysgenesis.

Research Areas: Cell Biology

Target Protein: SH3GLB2

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Endophilin B2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 43974

UniProt Accession: Human: Q9NR46; Mouse: Q8R3V5; Rat: Q5PPJ9

Synonyms: SH3GLB2; KIAA1848; PP578; Endophilin-B2; SH3 domain-containing GRB2-like protein B2

GeneID: Human: 56904; Mouse: 227700; Rat: 311848

Research Use Only