Endothelin B Receptor Polyclonal Antibody - BT-AP15402

Endothelin B Receptor Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15402-20, BT-AP15402-50, BT-AP15402-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.

Research Areas: Signal transduction

Target Protein: EDNRB

Applications: IHC-p, IF

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Endothelin B receptor

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P24530; Mouse: P48302; Rat: P21451

Synonyms: Endothelin B receptor;ET-B;ET-BR;Endothelin receptor non-selective type; Endothelin B receptor; ET-B; ET-BR; Endothelin receptor non-selective type

GeneID: Human: 1910

Research Use Only