EphB4 Monoclonal Antibody - BT-MCA2403

EphB4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2403-50, BT-MCA2403-100

Citations, Manuals and MSDS Available upon request.

Background: EphB4: EPH receptor B4. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Research Areas: Cardiovascular

Target Protein: EphB4

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7H4A6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: EphB4

Immunogen: Purified recombinant fragment of EphB4 (aa562-612)expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 108kDa

UniProt Accession: P54760

Synonyms: HTK, MYK1, TYRO11

GeneID: 2050

Research Use Only