EphB6 Monoclonal Antibody - BT-MCA3440

EphB6 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3440-50, BT-MCA3440-100

Citations, Manuals and MSDS Available upon request.

Background: EPH receptor B6 (EphB6), with 1006-amino acid protein(~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.

Research Areas: Neuroscience

Target Protein: EphB6

Applications: WB, IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8E7H12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: EphB6

Immunogen: Purified recombinant fragment of EphB6 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS containing 0.03% sodium azide.

UniProt Accession: O15197

Synonyms: HEP, MGC129910, MGC129911

GeneID: 2051

Research Use Only