FAK Monoclonal Antibody - BT-MCA2728

FAK Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2728-50, BT-MCA2728-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This cellular localization is directed by a

Research Areas: Others

Target Protein: FAK

Applications: ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 10H7E9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: FAK

Immunogen: Purified recombinant fragment of human FAK expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 119kDa

UniProt Accession: Q05397

Synonyms: FAK, FADK, FAK1, FRNK, pp125FAK, PTK2

GeneID: 5747

Research Use Only