FAK Monoclonal Antibody - BT-MCA2921

FAK Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2921-50, BT-MCA2921-100

Citations, Manuals and MSDS Available upon request.

Background: Focal adhesion kinase(FAK), with 1074 -amino acid protein(about 118 kDa), is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, and is activated and localized to the focal adhesions of spreading keratinocytes in culture. Thus, it has been postulated that FAK may have an important in vivo role in the re-epithelialization of human wounds. FAK protein tyrosine kinase activity has also been shown to increase in cells stimulated to grow by use of mitogenic neuropeptides or neurotransmitters acting through G protein-coupled receptors.

Research Areas: Others

Target Protein: FAK

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4A9D6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: FAK

Immunogen: Purified recombinant fragment of FAK expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: Q05397

Synonyms: FAK, FADK, FAK1, pp125FAK, PTK2

GeneID: 5747

Research Use Only