Product Description

FAM107A Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-91553-60, E-AB-91553-120, E-AB-91553-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: FAM107A

Target Synonym: FAM107A; DRR1; TU3A

Research Areas: Cancer, Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O95990

Background: Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity. Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human FAM107A

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 15kDa/17kDa/20kDa

Observed MW: 18kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only