FAM111B Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-19841-60, E-AB-19841-120, E-AB-19841-200 Citations, Manuals and MSDS Available upon request. Abbreviation: FAM111B Target Synonym: Cancer associated nucleoprotein; CANP ; Protein FAM111B Research Areas: Cell Biology Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human Application: IHC, ELISA Isotype: IgG Clonality: Polyclonal UNIProt ID: Q6SJ93 Background: This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. Concentration: 1.5 mg/mL Immunogen: Synthetic peptide of human FAM111B Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 Purification Method: Antigen affinity purification Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000 Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only