FAP Polyclonal Antibody-BS66175

FAP Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS66175-50, BS66175-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q12884

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF/ICC

All Applications: WB: 1:500-1:1000
IHC: 1:100-1:200
IF/ICC: 1:100-1:500

Background: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FAP polyclonal antibody detects endogenous levels of FAP protein.

Bioworld Molecular Weight: ~ 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FAP alpha expression in PC3 (A), H9C2 (B), CT26 (C), Hela (D) whole cell lysates., Immunohistochemical analysis of FAP alpha staining in human prostate cancer formalin fixed paraffin embedded tissue section., Immunofluorescent analysis of FAP alpha staining in HeLa cells.

Alternative Name: FAP; DPPIV; FAPA; FAPalpha; SIMP

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FAP.

Conjugate: Unconjugated

Modification: Unmodified