Fascin 1 Polyclonal Antibody - BT-AP03163

Fascin 1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03163-20, BT-AP03163-50, BT-AP03163-100

Citations, Manuals and MSDS Available upon request.

Background: FSCN1 encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The fascin actin-bundling protein 1 plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Research Areas: Signal Transduction

Target Protein: FSCN1

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Fascin 1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 54230

UniProt Accession: Human: Q16658; Mouse: Q61553; Rat: P85845

Synonyms: FSCN1; FAN1; HSN; SNL; Fascin; 55 kDa actin-bundling protein; Singed-like protein; p55

GeneID: Human: 6624; Mouse: 14086; Rat: 683788

Research Use Only