FBLN5 Monoclonal Antibody - BT-MCA2065

FBLN5 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2065-50, BT-MCA2065-100

Citations, Manuals and MSDS Available upon request.

Background: FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.

Research Areas: Signal Transduction

Target Protein: FBLN5

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1G6A4

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: FBLN5

Immunogen: Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: Q9UBX5

Synonyms: EVEC, UP50, ARMD3, DANCE

GeneID: 10516

Research Use Only