Product Description

FGFR1 OP (N371) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1123-50, BS1123-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: FOP, also known as FGFR1OP (FGFR1 oncogene partner), is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubμles to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia andμltimately leads to acute myeloid leukemia. FOP is expressed as mμltiple isoforms that are produced by alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC, IF

Alternate Names: FGFR1 oncogene partner,
FGFR1OP,
Fibroblast growth factor receptor 1 oncogene partner, FOP

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 341-390 of Human FGFR1 OP.

Dilution: IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).

Specificity: FGFR1OP (N371) polyclonal antibody detects endogenous levels of
FGFR1OP protein.

Molecular Weight: ~ 43, 92 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.

SwissProt: O95684

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only